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Bioorganic and Medicinal Chemistry Letters 12, 3583 3586.
Papahatjis, D.P., Nikas, S.P., Kourouli, T., Chari, R., Xu, W., Pertwee, R.G., Makriyannis, A., 2003. Pharmacophoric
requirements for the cannabinoid side chain. Probing the cannabinoid receptor subsite at C1V. Journal of Medicinal
Chemistry 46, 3221 3229.
Pertwee, R.G., 1997. Pharmacology of cannabinoid CB1 and CB2 receptors. Pharmacology and Therapeutics 74,
129 180.
Pertwee, R.G., 2000. Neuropharmacology and therapeutic potential of cannabinoids. Addiction Biology 5, 37 46.
Pertwee, R.G., Ross, R.A., Craib, S.J., Thomas, A., 2002. ( )-Cannabidiol antagonizes cannabinoid receptor agonists and
noradrenaline in the mouse vas deferens. European Journal of Pharmacology 456, 99 106.
Reggio, P.H., Wang, T., Brown, A.E., Fleming, D.N., Seltzman, H.H., Griffin, G., Pertwee, R.G., Compton, D.R., Abood,
M.E., Martin, B.R., 1997. Importance of the C-1 substituent in classical cannabinoids to CB2 receptor selectivity:
synthesis and characterization of a series of O,2-propano-D8-tetrahydrocannabinol analogs. Journal of Medicinal Chemistry
40, 3312 3318.
Reggio, P.H., Basu-Dutt, S., Barnett-Norris, J., Castro, M.T., Hurst, D.P., Seltzman, H.H., Roche, M.J., Gilliam, A.F.,
Thomas, B.F., Stevenson, L.A., Pertwee, R.G., Abood, M.E., 1998. Derivation of a pharmacophore model for anandamide
using constrained conformational searching and comparative molecular field analysis. Journal of Medicinal Chemistry 41,
5177 5187.
Rinaldi-Carmona, M., Barth, F., Heaulme, M., Shire, D., Calandra, B., Congy, C., Martinez, S., Maruani, J., Neliat, G., Caput,
D., Ferrara, P., Soubrie, P., Breliere, J.C., Le Fur, G., 1994. SR141716A, a potent and selective antagonist of the brain
cannabinoid receptor. FEBS Letters 350, 240 244.
Rinaldi-Carmona, M., Barth, F., Heaulme, M., Alonso, R., Shire, D., Congy, C., Soubrie, P., Breliere, J.C., Le Fur, G., 1995.
Biochemical and pharmacological characterisation of SR141716A, the first potent and selective brain cannabinoid receptor
antagonist. Life Sciences 56, 1941 1947.
Rinaldi-Carmona, M., Barth, F., Millan, J., Derocq, J.M., Casellas, P., Congy, C., Oustric, D., Sarran, M., Bouaboula, M.,
Calandra, M., Portier, M., Shire, D., Breliere, J.C., Le Fur, G., 1998. SR 144528, the first potent and selective antagonist of the
CB2 cannabinoid receptor. Journal of Pharmacology and Experimental Therapeutics 284 (2), 644 650.
Ruiu, S., Pinna, G.A., Marchese, G., Mussinu, J.-M., Saba, P., Tambaro, S., Casti, P., Vargiu, R., Pani, L., 2003. Synthesis and
characterization of NESS 0327: a novel putative antagonist of the CB1 cannabinoid receptor. Journal of Pharmacology and
Experimental Therapeutics 306, 363 370.
Ryan, W., Singer, M., Razdan, R.K., Compton, D.R., Martin, B.R., 1995. A novel class of potent tetrahydrocannabinols
(THCS): 2 -yne-delta 8- and delta 9-THCS. Life Sciences 56, 2013 2020.
Seltzman, H.H., Fleming, D.N., Thomas, B.F., Gilliam, A.F., McCallion, D.S., Pertwee, R.G., Compton, D.R., Martin, B.R.,
1997. Synthesis and pharmacological comparison of dimethylheptyl and pentyl anandamide analogs. Journal of Medicinal
Chemistry 40, 3626 3634.
1798 L.W. Padgett / Life Sciences 77 (2005) 1767 1798
Shim, J.-Y., Welsh, W.J., Cartier, E., Edwards, J.L., Howlett, A.C., 2002. Molecular interaction of the Antagonist N-(piperidin-
1-yl)-5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide with the CB1 cannabinoid receptor.
Journal of Medicinal Chemistry 45, 1447 1459.
Showalter, V.M., Compton, D.R., Martin, B.R., Abood, M.E., 1996. Evaluation of binding in a transfected cell line expressing a
peripheral cannabinoid receptor (CB2): identification of cannabinoid receptor subtype selective ligands. Journal of
Pharmacology and Experimental Therapeutics 278, 989 999.
Song, Z.H., Bonner, T.I., 1996. A lysine residue of the cannabinoid receptor is critical for receptor recognition by several
agonists but not WIN55212-2. Molecular Pharmacology 49, 891 896.
Tarzia, G., Duranti, A., Tontini, A., Spadoni, G., Mor, M., Tivara, S., Plazzi, P.V., Kathuria, S., Piomelli, D., 2003. Synthesis
and structure activity relationships of a series of pyrrole cannabinoid receptor agonists. Bioorganic and Medicinal
Chemistry 11, 3965 3973.
Thakur, G.A., Palmer, S.L., Harrington, P.E., Stergiades, I.A., Tius, M.A., Makriyannis, A., 2002. Enantiomeric resolution of a
novel chiral cannabinoid receptor ligand. Biochemical and Biophysical Methods 54, 415 422.
Thomas, B.F., Gilliam, A.F., Burch, D.F., Roche, M.J., Seltzman, H.H., 1998. Comparative receptor binding analyses of
cannabinoid agonists and antagonists. Journal of Pharmacology and Experimental Therapeutics 285, 285 292.
Thomas, A., Ross, R.A., Saha, B., Mahadevan, A., Razdan, R.K., Pertwee, R.G., 2004. 6U-Azidohex-2U-yne-cannabidiol: a
potential neutral, competitive cannabinoid CB1 receptor antagonist. European Journal of Pharmacology 487, 213 221.
Tius, M.A., Hill, W.A., Zou, G., Busch-Petersen, X.L., Kawakami, J., Fernandez-Garcia, J.K., Drake, M.C., Abadji, D.J.,
Makriyannis, V., 1995. Classical/non-classical cannabinoids hybrids; stereochemical requirements for the southern
hydroxyalkyl chain. Life Sciences 56, 2007 2012.
Tong, W., Collantes, E.R., Welsh, W.J., Berglund, B.A., Howlett, A.C., 1998. Derivation of a pharmacophore model for
anandamide using constrained conformational searching and comparative molecular field analysis. Journal of Medicinal
Chemistry 41, 4207 4215.
Wiley, J.L., Compton, D.R., Dai, D., Lainton, J.A.H., Phillips, M., Huffman, J.W., Martin, B.R., 1998. Structure activity
relationships of indole- and pyrrole-derived cannabinoids. Journal of Pharmacology and Experimental Therapeutics 285,
995 1004.
Wiley, J.L., Jefferson, R.G., Grier, M.C., Mahadevan, A., Razdan, R.K., Martin, B.R., 2001. Novel pyrazole cannabinoids:
insights into CB1 receptor recognition and activation. Journal of Pharmacology and Experimental Therapeutics 296,
1013 1022.
Wiley, J.L., Beletskaya, I.D., NG, E.W., Dai, Z., Crocker, P.J., Mahadevan, A., Razdan, R.K., Martin, B.R., 2002. Resorcinol
Derivatives: A novel template for the development of cannabinoid CB1/CB2 and CB2 selective agonists. Journal of
Pharmacology and Experimental Therapeutics 301, 679 689. [ Pobierz całość w formacie PDF ]

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